| 170 | 1 | St Thomas Aquinas Secondary School | London | Catholic | 7.7 | 7.7 | 7.5 | 6.8 | +0.9 ↑ | Visit |
| 246 | 2 | Mother Teresa Catholic Secondary School | London | Catholic | 7.3 | 7.3 | 7.1 | 7.2 | +0.1 ↑ | Visit |
| 310 | 3 | St. Andre Bessette Secondary School | London | Catholic | 7.1 | 7.1 | 7.3 | 6.8 | +0.3 ↑ | Visit |
| 342 | 4 | St Joseph's High School | St. Thomas | Catholic | 6.9 | 6.9 | 6.9 | 5.9 | +1.0 ↑ | Visit |
| 381 | 5 | Catholic Central High School | London | Catholic | 6.7 | 6.7 | 6.6 | 6.0 | +0.7 ↑ | Visit |
| 452 | 6 | St Mary's High School | Woodstock | Catholic | 6.4 | 6.4 | 5.9 | 5.8 | +0.6 ↑ | Visit |
| 464 | 7 | Holy Cross Catholic Secondary School | Strathroy | Catholic | 6.3 | 6.3 | 6.7 | 5.8 | +0.5 ↑ | Visit |
| 657 | 8 | Regina Mundi College | London | Catholic | 5.3 | 5.3 | 5.6 | 4.6 | +0.7 ↑ | Visit |
| 689 | 9 | John Paul II Catholic Secondary School | London | Catholic | 4.9 | 4.9 | 5.3 | 5.2 | -0.3 ↓ | Visit |
| 795 | 10 | LDCSB Online School High School | London | Catholic | — | — | — | — | — | — |